How many blood tuberculin tests are FDA-approved?

The correct answer is that there are two FDA-approved blood tuberculin tests. These tests, known as interferon-gamma release assays (IGRAs), are designed to detect tuberculosis (TB) infection by measuring the immune response to specific TB antigens. The tests provide an alternative to the traditional tuberculin skin test and are particularly useful in certain populations, such as those who have had the Bacillus Calmette-Guérin (BCG) vaccine or who may not return for a reading of a skin test.

In addition to being FDA-approved, IGRAs have been validated in different settings and populations, which contributes to their acceptance in clinical practice. They are advantageous because they do not require a follow-up visit for reading, unlike the skin test, making them more convenient for both patients and healthcare providers.

Understanding the significance of these two approved tests helps healthcare professionals make informed decisions regarding TB screening and diagnosis, particularly in individuals at high risk for latent TB infection.