Why should enteric-coated tablets not be crushed?

Enteric-coated tablets are specifically designed with a protective coating that prevents the tablet from dissolving in the acidic environment of the stomach. Instead, this coating allows the tablet to pass into the intestines where it can dissolve and be absorbed in a more suitable pH level. Crushing these tablets removes this protective coating, potentially leading to premature dissolution in the stomach, which can result in various issues. These issues may include irritation of the stomach lining, reduced efficacy of the medication, or altered absorption rates that could impact the patient's treatment plan.

The other options do not accurately capture the primary reason behind the contraindication of crushing enteric-coated tablets. For instance, crushing them does not pertain to the speed of relief or their effectiveness in combination with food, nor is it related to the difficulty in swallowing. Therefore, maintaining the integrity of the enteric coating is crucial for the intended therapeutic effect of these medications.